23rd International Conference on Gastroenterology, Hepatology & Endoscopy
London, UK
Mungwete Josue
Department of gastroenterology,Congo
Title: Screening for metabolic hepatic steatopathy by fibroscan, in type 2 diabetics in the Ivory Coast
Biography
Biography: Mungwete Josue
Abstract
Metabolic hepatic steatopathy is a major public health problem. Type 2 diabetics have a significant risk of developing NAFLD with a higher morbidity and mortality rate than non-diabetic subjects. Fibroscan/ CAP is a good diagnostic and prognostic tool for metabolic steatopathy, the aim of this study was to screen for metabolic hepatic steatopathy by fibroscan/CAP in diabetic subjects in Ivory Coast. Materials and methods Descriptive and analytical cross-sectional study carried out from February 1 to August 31, 2020 in two medical structures in Abidjan. Included in the study were diabetic patients, aged at least 18 years, who had performed a fibroscan/CAP associated whith clinical, biological and morphological evaluation.
Results
We included 520 patents whose age was 51.3+/- years (range 28years and 71years) with a sex ratio of 0.62. The patients had hypertension in 56,6% of cases, insulin resistance in 53,8% of cases, a diabetic complication in 48.1% of cases and dyslipidemia in 17.3% of cases. The prevalence of hepatic steatopathy evaluated by fibroscan /CAP in diabetics was 53.8%, distributed as follows: 3.8% S1 steatosis, 34,6% S2 steatosis and 19.2% S3 steatosis. The prevalence of hepatic steatopathy evaluated by fibroscan/ CAP in diabetics was 53.8%, distributed as follows : 3,8% S1 steatosis, 34.6% S2 steatosis and 19.2% S3 steatosis.
The patients had insignificant fibrosis in 51% and moderate or severe fibrosis in 49.1%. The steatopathy of our patients was associated with arterial hypertension (p = 0,02), insulin resistance (p = 0,003), BMI greater than 28,8 (p = 0,02), an increase moderate ALT (p = 0,001) and GGT (p = 0,001). The only independent factor associated with steatopathy in our patients was elevation of GGT.
Conclusion : Metabolic hepatic steatopathy is common in type 2 diabetics in Ivory Coast; Fibroscan /CAP is a good diagnostic and prognosis for steatopathy and hepatic fibrosis in these patients.
Keywords : metabolic steatopathy, diabetes, fibroscan/ CAP, Sub-Saharan Africa