Newton-Teixeira-dos-Santos
Federal university, Brazil
Title: Efficacy and Safety of Intragastric Balloon for Obesity and Pre-Obese Patients: A Brazilian Experience
Biography
Biography: Newton-Teixeira-dos-Santos
Abstract
The development of silicone gastric balloon filled with saline has significant results in treatment of obesity and, recently, it shows to be effective in pre-obese patients. To evaluate the safety and efficacy of Silimed Gastric Balloon (SGB) in pre-obese patients and patients with different grades of obesity. From september of 2007 to january of 2009, 84 patients who were unable to lose weight using clinical treatment were treated with SGB. The balloon was filled with 700 ml of a saline solution and 2% methylene blue, and was positioned on gastric fundus, under sedation. atients were divided among the body mass index (BMI) in 4 grades: pre-obese (BMI < 30 Kg/m2), obesity grade 1 (BMI 30-34.9), obesity grade 2 (BMI 35-39.9) and obesity grade 3 (BMI ≥ 40). They were followed in a multidisciplinary clinic setting for 5 to 7 months. Informed consents was obtained. The paired t test was used to evaluated the effectiveness of the proposed treatment. To compare the relative weight loss between the different grades of obesity we used the ANOVA one way. 81 patients completed the study. 2 patients were excluded because of spontaneous balloon deflation. 1 patient complicated with gastric laceration treated with surgery. Patients mean age was 38 (18-68) year and 61 was female (75.3%).The initial mean weight and mean BMI, respectively, were 100 Kg (range 69-171) and 36 Kg/m2 (range 27.6-65.6). The final mean weight and BMI were, respectively, 90.6 Kg (range 58-151) and 32.6 Kg/m2 (range 22.8-52.2). There were significant weight loss at the final of the treatment, mean absolute weight loss was 9.37 Kg (9.18% of initial weight) (p= 0.0001). When we evaluated the different groups of obesity we observed that there were significant weight loss in all groups, with no significant difference at the relative weight loss at the groups (p=0.061)(table 1). There were no endoscopic complications or failed balloon extractions. The SGB is a safe and effective alternative to the treatment of weight loss. All patients loose weight despite of the grade of obesity. There were only 2 cases of balloon deflation, but without bowel obstruction. The only major complication occurred in one alcoholic patient that omit this information.